Apoptosis Reagents and Kits
Echelon Biosciences Research Labs Caspase 13 Inhibitor - 5 mg,
Caspase 13 Inhibitor - 5mg , Ac-Leu-Glu-Glu-Asp-CHO Category/Application: Caspase Inhibitor This item is non returnable
Cytek Biosciences Inc APC Annexin V Apoptosis Detection Kit with 7-AAD
APC Annexin V Apoptosis Detection Kit with 7-AAD ..... Cat. No. 20-6410-KIT ..... Size KIT
CPC Scientific Ac-Trp-Glu-His-Asp-CHO (trifluoroacetate salt) 1MG
Very potent reversible inhibitor of caspase-1 (ICE) that contains the optimal tetrapeptide recognition motif for this enzyme. With a Ki of 56 pM, it displays the most potent reversible, peptide-based inhibitors described for any protease. For caspase-8 a Ki of 21.1 nM has been reported.SEQUENCE: Ac-Trp-Glu-His-Asp-CHO (trifluoroacetate salt)ONE-LETTER SEQUENCE: Ac-WEHD-CHOMOLECULAR FORMULA: C28H33N7O9MOLECULAR WEIGHT: 611.61STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: [189275-71-6]SYNONYMS: Ac-Trp-Glu-His-Asp-aldehyde (pseudo acid)RESEARCH AREA: ApoptosisREFERENCES:T.A. Rano, T. Timkey, E.P. Peterson, J. Rotonda, D.W. Nicholson, J.W. Becker, K.T. Chapman, and N.A. Thornberry, Chem. Biol., 4, 149 (1997).M. Garcia-Calvo, E.P. Peterson, B. Leiting, R. Ruel, D.W. Nicholson, and N.A. Thornberry, J. Biol. Chem., 273, 32608 (1998).SKU(s): CASP-004A
Abcam Annexin V-iFluor 594 Apoptosis Staining / Detection Reagent.
Annexin V-iFluor 594 Apoptosis Staining / Detection Reagent.
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology FLCN Rabbit pAb
This gene is located within the Smith-Magenis syndrome region on chromosome 17. Mutations in this gene are associated with Birt-Hogg-Dube syndrome, which is characterized by fibrofolliculomas, renal tumors, lung cysts, and pneumothorax. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Medchemexpress LLC Annexin A1/ANXA1 Mo 1mg
Annexin A1 (ANXA1) Protein, Mouse (His) is a full-length recombinant mouse annexin A1 expressed in Escherichia coli with an N-terminal 6xHis tag, supplied as a lyophilized powder. The protein is >95% pure, has an approximate molecular weight of 40 kDa, and low endotoxin (<1 EU/μg); it is formulated with trehalose for stability and intended for in vitro studies of inflammation, immune signaling, phagocytosis, and chemotaxis.
- Full-length recombinant protein with N-terminal His tag.
- Expressed in Escherichia coli for scalable production.
- Purity greater than 95% by reducing SDS-PAGE.
- Approximately 40 kDa molecular weight.
- Low endotoxin level (<1 EU/μg) suitable for cell-based assays.
- Lyophilized formulation with trehalose for enhanced stability.
- Demonstrated biological activity in suppressing TNF-alpha secretion in RAW264.7 cells.
- Multiple size options available to fit experimental needs.
Abcam Human DAB2 knockout HeLa cell lysate.
Human DAB2 knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
CPC Scientific Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Val-Ala-Asp-CHO 1MG
ONE-LETTER SEQUENCE: Ac-AAVALLPAVLLALLAPVAD-CHOMOLECULAR FORMULA: C88H151N19O22MOLECULAR WEIGHT:1827.3STORAGE CONDITIONS: -20 5CRESEARCH AREA: ApoptosisREFERENCES: N.A. Thornberry, and Y. Lazebnik, Science 281, 1312 (1998); Y-Z Lin, et al., J. Biol. Chem., 271, 5305 (1996); Y-Z Lin, et al., J. Biol. Chem., 270, 14255 (1995)
Abcam Human UBE2C knockout HeLa cell lysate.
Human UBE2C knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human IFNGR1 knockout HeLa cell lysate.
Human IFNGR1 knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical QPlexAutoANTIBDY DetectIo 96
An activator of the STING pathway induces secretion of IFN-B in human PBMCs (EC50 130 nM) increases serum levels of Ifn-B Il-6 Tnf and Cxcl1 in wild-type but not Sting-/- mice at 2.5 mg/kg inhibits the cytopathic effect of HCoV-229E in infected MRC-5 cells (EC50 3 nM) decreases the level of SARS-CoV-2 RNA in primary human bronchial airway epithelial cells in an air-liquid interface assay decreases tumor volume and increases survival in a CT26 murine colorectal cancer model at 3 mg/kg this compound is expected to exist in one or both tautomeric forms
Selleck Chemical LLC Z-VAD(OH)-FMK (Caspase Inhibitor VI) 5mg 161401-82-7
Z-VAD-FMK (Caspase Inhibitor VI) is an irreversible pan-caspase inhibitor. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Apexbio Technology LLC Z-WEHD-FMK(Synonyms: Z-WEHD fluoromethyl ketone, Z-WEHD-FMK inhibitor, Caspase-5 inhibitor Z-WEHD-FMK), 1mg, CAS: 210345-00-9.
Z-WEHD-FMK (CAS 210345-00-9) is a peptide-based inhibitor primarily targeting inflammatory caspases including caspase-1 -4 and -5 It irreversibly blocks caspase-mediated proteolytic cleavage interfering with cellular signaling pathways involved in inflammation and apoptosis Studies demonstrate that Z-WEHD-FMK treatment prevents Chlamydia-induced fragmentation of the Golgi apparatus by inhibiting golgin-84 cleavage thereby decreasing bacterial proliferation and altering lipid trafficking to pathogen-containing inclusions This inhibitor is frequently utilized in cell biology and infectious disease research to investigate caspase-related cellular processes and microbial pathogenesis mechanisms
Abcam Human BECN1 (Beclin 1) knockout HeLa cell lysate.
Human BECN1 (Beclin 1) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement